Página web de difusión de resultados del proyecto de investigación CTQ2015-65040-P: "Compuestos organometálicos: Aplicaciones como metalofármacos y en catálisis asimétrica".

Índice

Publicaciones derivadas del proyecto (títulos en verde reviews o capítulos de libro).

estructura

55. Evaluation of trypanocidal properties of ferrocenyl and cyrhetrenyl N-acylhydrazones with pendant 5-nitrofuryl group. Patricia M. Toro, Francisco Peralta, Juan Oyarzo, Shane R. Wilkinson, Mónica Zavala, Rodrigo Arancibia, Mauricio Moncada-Basualto, Iván Brito, Jonathan Cisterna, A. Hugo Klahn, Concepción López. Journal of Inorganic Biochemistry 219 (2021) 111428. DOI: 10.1016/j.jinorgbio.2021.111428. Full text.
54
. Pyridine- and Quinoline-Derived Imines as N,N‑Bidentate Directing Groups in Palladium versus Platinum C−H Bond Activation Reactions. Héctor Torralvo, Joan Albert, Xavier Ariza, Merce  Font-Bardia, Jordi Garcia, Jaume Granell, and Manuel Martinez. Organometallics 2021, 40, 203−217. DOI: 10.1021/acs.organomet.0c00703. Full text.
53
. Expanding the Range of Pyrenylphosphines and Their Derived Ru(II)-Arene Complexes. Laia Rafols, Sara Torrente, David Aguila , Vanessa Soto-Cerrato, Ricardo Pérez-Tomás, Patrick Gamez, and Arnald Grabulosa. Organometallics 2020, 39, 2959−2971. DOI: 10.1021/acs.organomet.0c00302. Full text.
52
. Novel multifunctional and multitarget homo- (Fe2) and heterobimetallic [(Fe,M) with M = Re or Mn] sulfonyl hydrazones. Yosselin Huentupil, Patricio Chung, Néstor Novoa, Rodrigo Arancibia, Pascal Roussel, Juan Oyarzo, A. Hugo Klahn, Carlos Silva, Carme Calvis, Ramon Messeguer, Ramón Bosque and Concepción López. Dalton Trans., 2020, 49, 12249. DOI: 10.1039/d0dt01756f. Full text.
51
. Self-Assembled, Highly Positively Charged, Allyl–Pd Crowns: Cavity-Pocket-Driven Interactions of Fluoroanions. Montserrat Ferrer, Albert Gallen, Albert Gutiérrez, Manuel Martínez, Eliseo Ruiz, Yvonne Lorenz, and Marianne Engeser. Chem. Eur. J. 2020, 26, 7847 – 7860. DOI: 10.1002/chem.202000316. Full text.

50
. Room-Temperature Phosphorescence and Efficient Singlet Oxygen Production by Cyclometalated Pt(II) Complexes with Aromatic Alkynyl Ligands. Ariadna Lázaro, Carla Cunha, Ramon Bosque, João Pina, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen, João Carlos Lima, Margarita Crespo, J. Sérgio Seixas de Melo, and Laura Rodríguez. Inorg. Chem. 2020, 59, 8220−8230. DOI: 10.1021/acs.inorgchem.0c00577. Full text.
49
. Palladium Complexes of Methylene-Bridged P‑Stereogenic, Unsymmetrical Diphosphines. Javier C. Córdoba, Anton Vidal-Ferran, Mercè  Font-Bardia, and Arnald Grabulosa. Organometallics 2020, 39, 2511−2525. DOI: 10.1021/acs.organomet.0c00283. Full text.
48
. Cyclopalladated Compounds with Polyhalogenated Benzylphosphanes for the Mizoroki-Heck Reaction. Cristina López-Mosquera, Arnald Grabulosa, Mercè Rocamora, Mercè Font-Bardia, and Guillermo Muller. Eur. J. Inorg. Chem. DOI: 10.1002/ejic.202000288. Full text.
47.
Luminescent PtII and PtIV Platinacycles with Anticancer Activity Against Multiplatinum-Resistant Metastatic CRC and CRPC Cell Models. Ariadna Lázaro, Cristina Balcells, Josefina Quirante, Josefa Badia, Laura Baldomà, Jas S. Ward, Kari Rissanen, Mercè Font-Bardia, Laura Rodríguez, Margarita Crespo and Marta Cascante. Chem. Eur. J. 2020, 26, 1947 – 1952. DOI: 10.1002/chem.201905325.
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46. Coordination chemistry and catalysis with secondary phosphine oxides. Albert Gallen, Antoni Riera, Xavier Verdaguer and Arnald Grabulosa. Catal. Sci. Technol., 2019, 9, 5504. DOI: 10.1039/c9cy01501a. Full text.
45.
Access to indolines from primary phenylethylamines by an unexpected palladium catalyzed C–H functionalization process. Andrea Mancinelli, Joan Albert, Xavier Ariza, Leoní A. Barrios, Jordi Garcia, Roberto Gómez and Jaume Granell. RSC Adv., 2019, 9, 27176. DOI: 10.1039/c9ra05670j. Full text.
44
. Cyclometallated ruthenium complexes with P-stereogenic monophosphines containing a polycyclic aromatic substituent. Arnald Grabulosa, Jaume Granell, Mercè Font-Bardia.
Journal of Organometallic Chemistry 896 (2019) 51-58. DOI: 10.1016/j.jorganchem.2019.05.015. Full text.
43
. Luminescence studies of new [C,N,N’] cyclometallated platinum(II) and platinum(IV) compounds. Ariadna Lázaro, Oriol Serra, Laura Rodríguez, Margarita Crespo and Mercè Font-Bardia. New J. Chem., 2019, 43, 1247. DOI: 10.1039/c8nj05492d.
Full text.
42. A novel type of organometallic 2-R-2,4-dihydro-1H-3,1-benzoxazine with R = [M(η5-C5H4)(CO)3] (M = Re or Mn) units. Experimental and computational studies of the effect of substituent R on ring-chain tautomerism. Juan Oyarzo, Ramón Bosque, Patricia Toro, Carlos P. Silva, Rodrigo Arancibia, Mercè Font-Bardía, Vania Artigas, Carme Calvis, Ramon Messeguer, A. Hugo Klahn  and Concepción López. Dalton Trans., 2019, 48, 1023. DOI: 10.1039/c8dt03265c. Full text.
41
. Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst. Ernest Salomo, Albert Gallen, Giuseppe Sciortino, Gregori Ujaque, Arnald Grabulosa, Agusti Lledos, Antoni Riera, and Xavier Verdaguer. J. Am. Chem. Soc. 2018, 140, 16967−16970. DOI: 10.1021/jacs.8b11547
. Full text.
40. Kinetico-mechanistic study on the reduction/complexation sequence of PtIV/PtII organometallic complexes by thiol-containing biological molecules. Margarita Crespo, Mercè Font-Bardia, Peyman Hamidizadeh, Manuel Martínez, S. Masoud Nabavizadeh. Inorganica Chimica Acta 486 (2019) 8–16. DOI: 10.1016/j.ica.2018.10.021. Full text.
39. Cyclometallated platinum(IV) compounds as promising antitumour agents.
Margarita Crespo. Journal of Organometallic Chemistry 879 (2019) 15-26. DOI: 10.1016/j.jorganchem.2018.10.008. Full text.

38
. Highly Cytotoxic Ruthenium(II)-Arene Complexes from Bulky 1‑Pyrenylphosphane Ligands. Rosa F. Brissos, Pau Clavero, Albert Gallen, Arnald Grabulosa, Leoní A. Barrios, Ana B. Caballero, Luís Korrodi-Gregório, Ricardo Pérez-Tomás,
Guillermo Muller. Inorg. Chem. 2018, 57, 14786−14797. DOI: 10.1021/acs.inorgchem.8b02541. Full text.
37
. Growth of Au−Pd2Sn Nanorods via Galvanic Replacement and Their Catalytic Performance on Hydrogenation and Sonogashira Coupling Reactions. Raquel Nafria, Zhishan Luo, Maria Ibáñez, Sara Martí-Sànchez, Xiaoting Yu, Maria de la Mata, Jordi Llorca, Jordi Arbiol, Maksym V. Kovalenko, Arnald Grabulosa, Guillermo Muller, and Andreu Cabot. Langmuir 2018, 34, 10634−10643. DOI: 10.1021/acs.langmuir.8b02023.
Full text. 
36.
Synthesis, characterization and biological activity of new cyclometallated platinum(IV) complexes containing a para-tolyl ligand. Mònica Solé, Cristina Balcells, Margarita Crespo,  Josefina Quirante, Josefa Badia, Laura Baldomà, Mercè Font-Bardia and Marta Cascante. Dalton Trans., 2018, 47, 8956. DOI: 10.1039/C8DT01124A. Full text.  
35.
Bond Dissociation Energies of Metallo-supramolecular Building Blocks: Insight from Fragmentation of Selectively Self-Assembled Heterometallic Metallo-supramolecular Aggregates. Yvonne Lorenz, Albert Gutiérrez, Montserrat Ferrer, and Marianne Engeser. Inorg. Chem. 2018, 57, 7346−7354. DOI: 10.1021/acs.inorgchem.8b00930. Full text.
34.
Design and synthesis of new antitumor agents with the 1,7-epoxycyclononane framework. Study of their anticancer action mechanism by a model compound. Ángel M. Montaña, Julia Lorenzo, Stefano Ponzano, Maria-Filomena Sanasi. Bioorganic & Medicinal Chemistry 26 (2018) 3379–3398. DOI: 10.1016/j.bmc.2018.05.009.
Full text.
33.
Platinacycles Containing a Primary Amine Platinum(II) Compounds for Treating Cisplatin-Resistant Cancers by Oxidant Therapy. Miguel Clemente, Ibrahim Halil Polat, Joan Albert, Ramon Bosque, Margarita Crespo, Jaume Granell, Concepción López, Manuel Martínez, Josefina Quirante, Ramon Messeguer, Carme Calvis, Josefa Badia, Laura Baldomà, Mercè Font-Bardia, and Marta Cascante. Organometallics 2018, 37, 3502−3514. DOI: 10.1021/acs.organomet.8b00206. Full text.
32.
A study of the properties, reactivity and anticancer activity of novel Nmethylated-3-thiazolyl or 3-thienyl carbazoles and their Pd(II) and Pt(II) complexes. Marta Reig, Ramón Bosque, Mercè Font-Bardía, Carme Calvis, Ramon Messeguer, Laura Baldomà, Josefa Badia, Dolores Velasco, Concepción López. Journal of Inorganic Biochemistry 184 (2018) 134–145. DOI: 10.1039/c8ob00194d. Full text.
31.
Synthesis and coordination chemistry of enantiopure t-BuMeP(O)H. Albert Gallen, Sílvia Orgué, Guillermo Muller, Eduardo C. Escudero-Adán, Antoni Riera, Xavier Verdaguer and Arnald Grabulosa. Dalton Trans., 2018, 47, 5366. DOI: 10.1039/c8dt00897c. Full text

30. Synthesis of the 10-oxabicyclo[5.2.1]decane. Ángel M. Montaña, Stefano Ponzano, Maria-Filomena Sanasid and Gabriele Kociok-Köhn. Org. Biomol. Chem., 2018, 16, 1557. DOI: 10.1039/c8ob00194d. Full text.
29. Reversible Self-Assembly of Water-Soluble Gold(I) Complexes. Elisabet Aguiló, Artur J. Moro, Raquel Gavara, Ignacio Alfonso, Yolanda Pérez, Francesco Zaccaria, Célia Fonseca Guerra, Marc Malfois, Clara Baucells, Montserrat Ferrer, João Carlos Lima and Laura Rodríguez. Inorg. Chem. 2018, 57, 1017−1028. DOI: 10.1021/acs.inorgchem.7b02343. Full text.
28
. Isomeric and hybrid ferrocenyl/cyrhetrenyl aldimines: a new family of multifunctional compounds. Juan Oyarzo, Alejandra Acuña, Hugo Klahn, Rodrigo Arancibia, Carlos P. Silva, Ramón Bosque, Concepción López, Mercè Font-Bardía, Carme Calvis and Ramón Messeguer. Dalton Trans., 2018, 47, 1635
. DOI: 10.1039/c7dt04142j. Full text.
27.
Mono and dinuclear bis(ortho-tolyl)platinum(II) compounds containing diethyl sulfide ligands: Synthesis, DFT studies and use as precursors in cycloplatination reactions. Ramon Bosque, Margarita Crespo, Anna Escola, Merce Font-Bardia. Journal of Organometallic Chemistry 854 (2018) 122-130. DOI: 10.1016/j.jorganchem.2017.11.020.
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26. Synthesis, characterization and biological activity of new cyclometallated platinum(IV) iodido complexes. Emma Bauer, Xavier Domingo, Cristina Balcells, Ibrahim H. Polat, Margarita Crespo, Josefina Quirante, Josefa Badia, Laura Baldomà, Mercè Font-Bardia and Marta Cascante. Dalton Trans., 2017, 46, 14973. DOI: 10.1039/c7dt03448b.
Full text.
25. Half-Sandwich Complexes of Ir(III), Rh(III) and Ru(II) with the MaxPhos Ligand: Metal Centred Chirality and Cyclometallation. Juan Téllez, Albert Gallen, Joaquina Ferrer, Fernando J. Lahoz, Pilar García-Orduña, Antoni Riera, Xavier Verdaguer, Daniel Carmona, and Arnald Grabulosa. Dalton Trans. DOI: 10.1039/C7DT03327C. Full text.
24
. Polypyridyl-functionalizated alkynyl gold(I) metallaligands supported by tri- and tetradentate phosphanes. Montserrat Ferrer, Leticia Giménez, Albert Gutiérrez, João Carlos Lima, Manuel Martínez, Laura Rodríguez, Avelino Martín, Rakesh Puttreddye and Kari Rissanen. Dalton Trans., 2017, 46,13920. DOI: 10.1039/c7dt02732j. Full text.

23.
Ángel M. Montana, Juan A. Barcia, Gabriele Kociok-Kohn, Mercè Font-Bardia CCDC 720949: Experimental Crystal Structure Determination, 2017, DOI: 10.5517/ccdc.csd.ccs66fl.

22
. The σ and π Holes. The Halogen and Tetrel Bondings: Their Nature, Importance and Chemical, Biological and Medicinal Implications. Á
ngel M. Montaña. ChemistrySelect 2017, 2, 9094 – 9112. DOI: 10.1002/slct.201701676. Full text.
21. Diarylplatinum(II) Scaffolds for Kinetic and Mechanistic Studies on the Formation of Platinacycles via an Oxidative Addition/Reductive Elimination/Oxidative Addition Sequence. Gabriel Aullón, Margarita Crespo, Jesús Jover, Manuel Martínez. Advances in Inorganic Chemistry. DOI: 10.1016/bs.adioch.2017.01.001.
20
. NH2- or PPh2-functionalized linkers for the immobilization of palladium on magnetite nanoparticles? Francisco J. Caparrós, Anderson Guarnizo, Marta D. Rossell, Inmaculada Angurell, Miquel Seco, Guillermo Muller, Jordi Llorca and Oriol Rossell. RSC Adv., 2017, 7, 27872. DOI: 10.1039/c7ra03639f. Full text.

19
. Endo and exo cyclopalladated (E)-N-([1,1'-biphenyl]-2-yl)-1-mesitylmethanimines: Anticancer, antibacterial and antioxidant activities. Joan Albert, Jaume Granell, Jose Antonio Duran, Adria Lozano, Anna Luque, Alicia Mate, Josefina Quirante, M. Kaleem Khosa, Carme Calvis, Ramon Messeguer, Laura Baldomà, Josefa Badia. Journal of Organometallic Chemistry 839 (2017) 116-125. DOI: 10.1016/j.jorganchem.2017.04.002.
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18. Preparation of Substituted Tetrahydroisoquinolines by Pd(II)-Catalyzed NH2‑Directed Insertion of Michael Acceptors into C−H Bonds Followed by NH2‑Conjugated Addition. Andrea Mancinelli, Carla Alamillo, Joan Albert, Xavier Ariza, Haizea Etxabe, Jaume Farràs, Jordi Garcia, Jaume Granell, and F. Javier Quijada. Organometallics 2017, 36, 911−919. DOI: 10.1021/acs.organomet.6b00944. Full text.
17. P-Stereogenic Phosphines for the Stabilisation of Metal Nanoparticles. A Surface State Study. Eva Raluy, Arnald Grabulosa, Pierre Lavedan, Christian Pradel, Guillermo Muller, Isabelle Favier, and Montserrat Gómez. Catalysts 2016, 6, 213. DOI: 10.3390/catal6120213. Full text.
16
. Palladium allylic complexes with enantiopure bis(diamidophosphite) ligands bearing a cyclohexane-1,2-diamine skeleton as catalysts in the allylic substitution reaction. Maritza J. Bravo, Rosa M. Ceder, Arnald Grabulosa, Guillermo Muller, Mercè Rocamora, Mercè Font-Bardia. Journal of Organometallic Chemistry 830 (2017) 42-55. DOI: 10.1016/j.jorganchem.2016.12.007.
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15
. Rhodium(I) macrocyclic and cage-like structures containing diphosphine bridging ligands. Julià Arcau, Montserrat Ferrer, Elisabet Aguiló, Laura Rodrıíguez. Transit Met Chem (2017) 42:57–67. DOI: 10.1007/s11243-016-0107-7.
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14. The influence of ancillary ligands on the antitumoral activity of new cyclometallated Pt(II) complexes derived from an ferrocene-pyrazole hybrid. Eva Guillen, Asensio Gonzalez, Pradipta K. Basu, Amrita Ghosh, Mercè Font-Bardia, Teresa Calvet, Carme Calvis, Ramon Messeguer, Concepción López. Journal of Organometallic Chemistry 828 (2017) 122-132. DOI: 10.1016/j.jorganchem.2016.11.03. Full text.
13.
Regio- and Stereoselective Synthesis of Acetallic Tetrahydropyrans as Building Blocks for Natural Products Preparation, via a Tandem [4+3]-Cycloaddition/Ozonolysis Process. Ángel M. Montaña, Albert Corominas, Juan F. Chesa, Francisca García, and Mercè Font-Bardia. Eur. J. Org. Chem. 2016, 4674–4695. DOI: 10.1002/ejoc.201600590. Full text.
12.
The molecular shape and the field similarities as criteria to interpret SAR studies for fragment-based design of platinum(IV) anticancer agents. Correlation of physicochemical properties with cytotoxicity. Julia Lorenzo, Ángel M. Montaña. Journal of Molecular Graphics and Modelling 69 (2016) 39–60. DOI: 10.1016/j.jmgm.2016.07.010.
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11
. New methodology for the synthesis of tetrahydrofuro[3,2-b]furan-2(3H)-one derivatives, synthons of natural products with biological interest Ángel M. Montaña, Joan A. Barcia, Pedro M. Grima, Gabriele Kociok-Köhn. Tetrahedron 72 (2016) 6794-6806. DOI: 10.1016/j.tet.2016.09.004.
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10. Synthetic methodology to prepare polysubstituted 2-aminopyrans. Synthesis of the C32-C38 subunit of immunosuppressant sanglifehrin A. Ángel M. Montaña, Joan Barcia, Albert Corominas. Tetrahedron 72 (2016) 4798-4812. DOI: 10.1016/j.tet.2016.06.045. Full text.
9.
On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions. Anna Escolà, Margarita Crespo, Concepción López, Josefina Quiranteb, Anusha Jayaraman, Ibrahim H. Polat, Josefa Badia, Laura Baldomà, Marta Cascante. Bioorganic & Medicinal Chemistry 24 (2016) 5804 - 5815
. DOI: 10.1016/j.bmc.2016.09.037. Full text.
8
. Neutral and Cationic Palladium Complexes of P-Stereogenic Phosphanes Bearing a Heterocyclic Substituent. Pau Clavero, Arnald Grabulosa, Mercè Rocamora, Guillermo Muller, and Mercè Font-Bardia.
Eur. J. Inorg. Chem. 2016, 4216 - 4225. DOI: 10.1002/ejic.201600608. Full text.
7
. Diphosphorus Ligands Containing a P-Stereogenic Phosphane and a Chiral Phosphite or Phosphorodiamidite – Evaluation in Pd-Catalysed Asymmetric Allylic Substitution Reactions. Pau Clavero, Arnald Grabulosa, Mercè Rocamora, Guillermo Muller, and Mercè Font-Bardia.
Eur. J. Inorg. Chem., 2016: 4054–4065. DOI: 10.1002/ejic.201600550. Full text.
6. Colorimetric and fluorescence “turn-on” recognition of fluoride by a maleonitrile-based uranyl salen-complex. Silvia Bartocci, Ferran Sabaté, Ramon Bosque, Flore Keymeulen, Kristin Bartik, Laura Rodríguez, Antonella Dalla Cort. Dyes and Pigments 2016, 135, 94–101. DOI: Full text.
5. Highly water-dispersible Pd nanoparticles and single atoms magnetite-supported as excellent catalysts for Suzuki and hydrogenation reactions. A. Guarnizo, I. Angurell, G. Muller, J. Llorca, M. Seco, O. Rossell, and M. D. Rossell. RSC Advances 2016, 6, 68675-68684. DOI: 10.1039/c6ra14257e. Full text.
4. Synthesis, characterization, crystal structures and computational studies on novel cyrhetrenyl hydrazones. Johana Gómez, Nelson Leiva, Rodrigo Arancibia, Juan Oyarzo, Gonzalo E. Buono-Core, A. Hugo Klahn, Vania Artigas, Mauricio Fuentealba, Ramon Bosque, Gabriel Aullón, Concepción López, Mercè Font-Bardía, Teresa Calvet. Journal of Organometallic Chemistry 2016, 819, 129–13. DOI:10.1016/j.jorganchem.2016.06.026. Full text.
3
. Magnetite-supported palladium single-atoms do not catalyse the hydrogenation of alkenes but small clusters. Marta D. Rossell, Francisco J. Caparrós, Inmaculada Angurell, Guillermo Muller, Jordi Llorca, Miquel Seco, and Oriol Rossell. Catal. Sci. Technol. 2016,6, 4081-4085. DOI: 10.1039/C6CY00596A.
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2
. Synthesis and crystal structure of the dinuclear cyclopalladated compounds of methyl (E)-4-(benzylideneamino)benzoate with acetato and chlorido bridge ligands: Study of their splitting reactions with pyridine. Joan Albert, Ramon Bosque, Lucía D'Andrea, José Antonio Durán, Jaume Granell, Mercè Font-Bardia, and Teresa Calvet. Journal of Organometallic Chemistry 2016, 815–816, 44–52. DOI: 10.1016/j.jorganchem.2016.05.003
. Full text.
1
. Ruthenium complexes of P-stereogenic phosphines with a heterocyclic substituent. Pau Clavero, Arnald Grabulosa, Mercè Rocamora, Guillermo Muller and Merce Font-Bardia. Dalton Trans. 2016, 45, 8513-8531. DOI: 10.1039/C6DT00995F. 
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